Tests for the Female

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The basic investigation and evaluation of Female Fertility is conducted in 3 axes: Through the clinical assessment and examination by a specialist Gynecologist, through laboratory testing (hormonal evaluation and pathogen detection) and through medical imaging methods (ultrasonography / salpingography) to determine physiology and function of the female reproductive system. Depending on the indications and the medical history of a woman, specialized examinations may be offered such as molecular testing, hematological and biochemical examinations, as also minimally invasive procedures such as hysteroscopy and laparoscopy may be required.

In addition to the ovarian function, the environment and the patency of the reproductive system, endometrial receptivity and other factors related to achieving and maintaining pregnancy, as well as minimizing the possible complications of pregnancy are examined. As the female body nurtures, protects and promotes the development of a novel genetic organism, it is important in collaboration and always under the guidance and supervision of the Gynecologist to safely perform all appropriate tests to protect the health of mother and fetus.

Fertility & Reproductive Function Testing

  • Basic Hormonal Profile: FSH, LH, E2, PRL, TSH, FT3, FT4
  • Comprehensive Hormonal Profile: FSH, LH, E2, PRL, TSH, FT3, FT4, DHEA-S, Δ4A, Free Testosterone, SHBG, 17-OH-Progesterone, Cortisol F
  • Anti-Müllerian Hormone (AMH): Assessment of ovarian reserve
  • Inhibin B: Assessment of ovarian sufficiency & function
  • Hormonal Disorders – Menstrual Cycle (Basic): FSH, LH, E2, PRL, TSH, FT3, FT4, Testosterone, DHEA, Δ4A, 17-OH-Progesterone, AMH
  • Hormonal Disorders – Menstrual Cycle (Comprehensive): FSH, LH, E2, PRL, TSH, FT3, FT4, Anti-TPO, Anti-TG, Free Testosterone, Testosterone, DHEA, DHEA-S, Δ4A, AMH, CA125, Hematocrit, Hemoglobin, Iron, Ferritin, Progesterone
  • Polycystic Ovary Syndrome Hormonal Profile (Basic): Δ4A, Free Testosterone, DHEA-S
  • Polycystic Ovary Syndrome Hormonal Profile (Comprehensive): Δ4A, Free Testosterone, DHEA-S, FSH, LH, PRL, E2, SHBG
  • Reproductive Wellness Markers
  • Thyroid Function: TSH, FT3, FT4, Anti-TPO, Anti-TG
  • Biochemical Thrombophilia Panel: Investigation of hematological infertility factors & recurrent miscarriage
  • Anti-Paternal Antibodies: Investigation of alloimmune causes of recurrent miscarriages (blood test in both partners)
  • Immunophenotyping of NK-T Cells: For infertility and immunological miscarriage cases

Molecular Tests

  • Karyotype (conventional and molecular – Array CGH)
  • Fragile X (FMR1) Testing
  • Cystic Fibrosis Mutations (99% of population variants)
  • Thrombophilia Genetic Testing (13 mutations)
  • Genetic Disease Testing: α & β Thalassemia, Achondroplasia, Hypochondroplasia, Congenital Adrenal Hyperplasia, Muscular Dystrophy, Hearing Loss
  • Carrier Screening (22 Genetic Disorders): alpha-/beta-Thalassemia, delta-beta Thalassemia, Cystic Fibrosis, Fragile X Syndrome, Non-Syndromic Hearing Loss (GJB2 & GJB6), Sickle-Cell Disease, Spinal Muscular Atrophy, Tay-Sachs, Bloom Syndrome, Canavan Disease, Duchenne/Becker Muscular Dystrophy, Familial Dysautonomia, Fanconi Anemia, Galactosemia, Gaucher Disease, Medium-Chain Acyl-CoA Dehydrogenase Deficiency, Mucolipidosis, Niemann-Pick Disease, Phenylalanine Hydroxylase Deficiency, Smith-Lemli-Opitz Syndrome
  • Structural Abnormalities/Deletions & Genetic Marker
  • Hereditary Cancer Panel: Breast, ovarian, endometrial, colorectal, pancreatic, gastric, thyroid, kidney, melanoma
Blood Tests
  • Preoperative Testing: CBC, Glucose, Urea, Serum Sodium, Serum Potassium, Prothrombin Time (PT), Activated Partial Thromboplastin Time (aPTT), Virology Panel (HIV I/II, HBsAg, anti-HCV, VDRL-RPR)
  • Complete Blood Count & Hematology
  • General Health Screening
  • General & Reproductive Wellness Screening
  • Virology Panel
  • Immunology Tests

Urine Tests

  • Urinalysis
  • Urine Culture
  • Molecular Pathogen Detection (PCR)
  • Molecular pathogen detection: Molecular identification of aerobic & anaerobic pathogens and molecular antibiotic susceptibility testing.
  • Urine Cytology
Vaginal Fluid, Cervical Smear & Endometrial Testing
  • Vaginal Fluid Culture: Direct microscopy, aerobic & anaerobic cultures, testing for Mycoplasma hominis, Ureaplasma urealyticum, Chlamydia trachomatis
  • Molecular pathogen detection: Molecular identification of aerobic & anaerobic pathogens and molecular antibiotic susceptibility testing.
  • STI Pathogen Detection by PCR: (Chlamydia trachomatis, Neisseria gonorrhoeae, Mycoplasma genitalium, Ureaplasma urealyticum, Ureaplasma parvum, Trichomonas vaginalis, Treponema pallidum, Mycoplasma hominis, Haemophilus ducreyi, Herpes Simplex Virus Type 1 & 2)
  • HPV PCR Typing: Detection & identification of 35 HPV strains (high- & low-risk)
  • Cervical Cytology: Conventional Pap smear or ThinPrep liquid-based cytology
  • Microbiome Analysis: Identification of symbiotic and pathogenic microorganisms via Next-Generation Sequencing (NGS)

Pregnancy

  • Pregnancy Confirmation: β-HCG (Beta-Human Chorionic Gonadotropin)
  • Prenatal Screening: Complete blood count & urinalysis, blood group & thalassemia screening, biochemical testing, virology panel, rubella, CMV & toxoplasmosis antibodies, glucose tolerance curve
  • Non-Invasive Prenatal Testing (NIPT): Panorama, Harmony